What Supplements Should I Take for Histamine Intolerance

High Histamine Foods

Histamine Intolerance: The Hidden Cause of Chronic Allergy-Like Reactions

Histamine intolerance is extremely common—so much so that I’d say that roughly 1 in 40 people on Earth are dealing with the chronic headaches, rashes, nasal congestion, digestive issues, anxiety, and fatigue characteristic of hidden histamine buildup. Such people have a real problem dealing with external immune triggers of any sort, whether from foods, environmental triggers, or even their own gut.

Common Symptoms of Histamine Intolerance

  • Unexplained skin reactions–flushing of the face, itching, or hives appearing for no clear reason.

  • Allergy-like nasal symptoms–bouts of sneezing or a runny/stuffy nose, especially in the morning or after certain meals (yet allergy tests often come back negative).

  • Digestive distress–episodes of bloating, abdominal pain, or diarrhea that come and go, often worse after eating fermented or aged foods.

  • Headaches or migraines–frequent headaches that get triggered by foods like vinegar or aged cheese, or even by stress and poor sleep.

  • “Wired but tired” feelings–a racing heart, anxiety or jitteriness (histamine is a stimulant), often followed by crashes of fatigue and brain fog.

  • Sleep disturbances–light, fragmented sleep or night-time insomnia (high histamine at night can keep you awake), leading to grogginess in the morning.

  • Sensitivity to alcohol and leftovers–getting disproportionate reactions (flushing, fast heartbeat, nausea) from even small amounts of alcohol or leftovers/high-histamine foods that others handle fine.

  • Feeling “overloaded” by normal life–a general sense that your body is overreactive and easily thrown off by foods, supplements, or environmental changes, even though standard medical tests show nothing obvious.

What Histamine Intolerance Is (and Why It Happens)

Histamine intolerance isn’t an “allergy” to histamine.

It’s essentially a state of histamine overload. In that sense, to call it an “intolerance” is really a misnomer. Histamine is a natural compound that your body produces (and that is also present in many foods) which plays roles in immunity, digestion, and the nervous system. Your body normally keeps histamine in check by breaking it down with specific enzymes. The main one is diamine oxidase (DAO), which is produced in the gut and acts like an “off-switch” for histamine coming in through food.

Another enzyme, histamine N-methyltransferase (HNMT), helps break down histamine inside the body (particularly in the brain). Under healthy conditions, these enzymes inactivate histamine at a normal pace so it doesn’t build up to problematic levels.

In histamine intolerance, that breakdown process is sluggish, and DAO is often the bottleneck:

If DAO enzyme activity is reduced or overwhelmed, histamine isn’t cleared as it should be. The result is an imbalance between how much histamine you’re accumulating versus how much you can eliminate, leading to a persistent excess of histamine in your system.

In simpler terms: DAO is supposed to be your biochemical off-switch for histamine (especially from food). When DAO isn’t working efficiently (or if you’re flooding your system with more histamine than usual), that off-switch fails. Histamine lingers and continues to stimulate receptors all over the body, causing ongoing issues–physiologically (inflammation, allergic-type reactions) and even mentally (since histamine is also a neurotransmitter that can provoke anxiety and insomnia).

Things That Trigger Histamine Excess

Several factors can trigger this state of histamine excess. For one, dietary sources of histamine can add a huge load: certain foods contain very high levels of histamine, and others can trigger your body to release histamine or even block DAO’s activity. For example, fermented and aged foods (like aged cheeses, cured meats, sauerkraut, vinegar, etc.) are rich in histamine themselves.

On top of that, alcohol (like wine) not only contains histamine but also impairs DAO’s function, effectively a double hit. Meanwhile, some foods don’t contain much histamine but are known as histamine liberators–they can prompt your mast cells to dump histamine. Common ones include tomatoes, citrus fruits, strawberries, pineapples, and shellfish. The result is that even a “healthy” meal of, say, spinach salad with tomatoes and fermented dressing could quietly load you up with histamine. If your DAO is sluggish, that histamine “bucket” fills faster than it can be emptied. Eventually it overflows into symptoms.

Why Most Doctors Still Miss Histamine Intolerance

Complicating matters, histamine intolerance is not an officially recognized medical condition in many circles. It’s sometimes referred to as a “pseudo-allergy” because the reactions look like allergies, but allergy tests (measuring IgE antibodies) come up empty. Mainstream medicine has been slow to acknowledge it–for instance, it’s not listed in the ICD-11 medical diagnostic codes. Most doctors still aren’t taught about it, or they consider it rare or unproven. In reality, it’s very real for those experiencing it (even if the research community is still catching up on the exact mechanisms). The lack of recognition means a lot of people get misdiagnosed with general labels like “IBS” or “migraine” or “anxiety” without anyone realizing histamine is the underlying issue. Histamine intolerance affects multiple organ systems and the symptoms can be bizarrely sporadic and nonspecific, which is one reason it’s missed so often. One day your skin is erupting in hives; the next day you’re totally fine there but instead you have a crushing migraine and flushing. Such wide-ranging effects often send patients on a wild goose chase from one specialist to another.

The DAO Gene: Why Some People Feel Histamine Intolerance More Than Others

Genetics Affect Histamine Intolerance

So why do some individuals seem to get totally zonked by histamine, while others can eat an entire pepperoni pizza (preserved meat + cheese) and feel just fine?

A big part of it comes down to genetics–especially genes involved in histamine breakdown. The key player here is the gene that encodes the DAO enzyme (called AOC1 in genetics terms). Just like some people have a “slow” version of the COMT enzyme (as in the well-known Val158Met COMT polymorphism), some people inherit a weak DAO enzyme. There are specific SNPs (single nucleotide polymorphisms) in the DAO/AOC1 gene that can reduce the enzyme’s activity or expression.

For example, one DAO gene variant known as rs2052129 has been linked to significantly lower DAO levels and a higher risk of histamine intolerance. If you happen to carry a genetic combination that yields subpar DAO function, you essentially start off life with a smaller histamine “bucket.” Your capacity to clear histamine is only, say, half or a quarter of what someone else might have. So histamine-containing foods or stressors will hit you much harder.

Likewise, genetic variants in the HNMT gene (the enzyme that breaks down histamine in the brain and other tissues) can play a role. A less efficient HNMT enzyme might mean your brain is more susceptible to histamine–potentially contributing to symptoms like headaches, anxiety, or sleep problems when histamine is high. It’s the same concept: your “off-switch” for histamine signals is genetically dimmed.

Beyond genetics, there are other factors that make certain people more prone to histamine issues. A big one is gender and hormones.

The Role of Estrogen and Hormones in Histamine Intolerance

Interestingly, roughly 80% of people with diagnosed histamine intolerance are women (often around age 40). Why? One theory is that estrogen and other hormonal differences modulate histamine. Estrogen can actually prompt mast cells to release more histamine, and it may also down-regulate DAO production. Women often report their histamine-related symptoms (like migraines or hives) fluctuate with their menstrual cycle–for instance, worsening in the late luteal phase when estrogen peaks and progesterone drops. There’s evidence that the cyclical hormone changes can influence DAO enzyme levels; if DAO doesn’t rise sufficiently before menstruation, a woman might experience more histamine overload symptoms premenstrually. This could also partly explain why some women suddenly develop histamine intolerance around perimenopause or after pregnancy, when hormone profiles shift.

Other Triggers: Medications and Gut Health

Certain medications and health conditions. Some drugs are known to inhibit DAO activity or trigger histamine release. For example, common pain relievers like NSAIDs, and acid-blocking drugs like PPIs (proton pump inhibitors), can interfere with DAO and have been implicated in histamine intolerance cases. Anti-depressants and other medications have also been suspected of raising histamine or lowering DAO. Meanwhile, chronic gastrointestinal issues are strongly associated with histamine problems. If you have conditions like IBS, SIBO (small intestine bacterial overgrowth), celiac disease, or inflammatory bowel disease, these can both increase histamine production (due to imbalanced gut flora and inflammation) and decrease DAO output (since DAO is made in the gut lining). In fact, some researchers view histamine intolerance as a secondary phenomenon often stemming from an unhealthy gut environment. Chronic gut inflammation or dysbiosis creates a perfect storm: more histamine is generated in the gut (certain bacteria produce histamine) and the damaged gut lining produces less DAO to break it down. It’s a double hit that can push someone who never had issues before into a histamine-intolerant state.

The bottom line here is that some people are naturally predisposed to histamine intolerance (due to genetics and sometimes gender/hormonal factors), whereas others may acquire it over time due to things like medication use, diet, and gut health. If you happen to draw the short straw genetically and you develop one of these exacerbating factors, that’s when histamine intolerance can go from mild to life-altering.

This Is Why Symptoms Build So Gradually:

Importantly, histamine intolerance usually doesn’t flip your life upside-down overnight. It tends to sneak up on people. I’d describe it as a threshold or “bucket” model: you might tolerate histamine just fine up to a point, until one day your bucket quietly overflows. At that tipping point, the symptoms that were occasional or subtle can snowball into a chronic, confusing illness.

Why does it often seem to come out of nowhere after years of no issues? One possible explanation is the gradual accumulation of histamine in the body over time, coupled with growing systemic inflammation that impairs your ability to clear it. You might steadily lose DAO activity (due to aging, nutrient deficiencies, or gut damage) or you might unknowingly increase your histamine load (say, by changing your diet or lifestyle) until a critical threshold is reached.

I see this pattern frequently: maybe you were completely fine eating whatever you wanted through your twenties. Then in your thirties you start getting random rashes or “hangover” like symptoms after seemingly normal foods–small red flags. In your forties, perhaps after a period of stress or a gut infection, suddenly you have daily headaches or panic attacks or IBS flares that seem to come out of the blue. In reality, the groundwork was being laid over years. Histamine intolerance often builds in a slow crescendo. One high-histamine meal or one tough day of stress doesn’t reset to zero the next day; instead, it adds to your cumulative histamine burden. If today’s histamine isn’t fully cleared before tomorrow’s arrives, you get a stacking effect. Eventually the load reaches a point where even minor exposures trigger noticeable symptoms.

Why the Symptoms Don’t Make Sense, At First:

Symptoms also tend to broaden and intensify with time. Initially, you might have just one quirky symptom–for example, after a sushi dinner (fish can be high in histamine), you get a flushing reaction. But everything else is fine. A few months later, you start getting sniffles and racing heart after your evening crackers and cheese. Fast forward, and now you wake up with facial flushing even on days you didn’t eat anything obviously high-histamine. Your sleep becomes restless most nights, not just occasionally. In other words, what was once an isolated issue morphs into a chronic pattern. One difficult day becomes two. One food sensitivity turns into a list of ten. One “off” night of insomnia becomes a string of sleepless weeks. And so on.

This slow progression is deceptive–both to patients and doctors. The human mind tends to look for one-to-one cause-and-effect (“I ate X and then I felt Y”), but with histamine intolerance the effects are cumulative and context-dependent. It’s easy to misattribute the cause to something else, or to not connect the dots at all. Many people suffer for years, treating each symptom in isolation–they take migraine meds for headaches, antacids for gut pain, anxiety meds for panic–never realizing there’s a common root. Because the symptoms span so many systems, histamine issues often get shrugged off as psychosomatic or “just aging” or a series of coincidental mild allergies. In truth, there is a real biochemical overload happening; it’s just gradual and multi-faceted. Research literature even notes that the manifestations are often sporadic and nonspecific, which makes histamine intolerance tricky to pin down.

The gradual nature also means people with histamine intolerance often adapt their life unknowingly to cope, further obscuring the diagnosis. You might start avoiding protein powders and cheeses because you “just don’t tolerate them anymore,” or you always carry antihistamines on spring days, or you find yourself needing more sleep than you used to–small adjustments that mask a brewing problem. It’s only when things get really out of balance that most seek help.

How to Address Histamine Intolerance (Without the Common Traps)

So, what do you do if this picture is sounding familiar? The encouraging news is that once you recognize histamine intolerance for what it is, you can take steps to get better.

People often can get dramatic improvements by implementing a targeted plan. However–and this is critical–you need to approach it in the right way. There are a few very common pitfalls that cause many well-intentioned efforts to fall flat (or even backfire). I’ll outline those in a moment. First, let’s talk about the effective strategies for taming histamine intolerance.

Step 1: Lower Your Histamine Exposure (At Least Temporarily)

The first logical step is to reduce the influx of histamine into your system, to stop feeding the fire. Practically, this means adopting a low-histamine diet for a period of time. By cutting out the biggest dietary histamine sources, you give your body a chance to catch up on breaking down the excess. In fact, studies show that a low-histamine diet is often the first step to reducing histamine intolerance symptoms. Many people notice improvement within just a few days or weeks of avoiding high-histamine foods, which can serve as confirmation that histamine was indeed a culprit. This makes sense: you’re relieving the immediate pressure on your system.

Which Foods Are High in Histamine?

Sauerkraut is high in histamine

What are the high-histamine foods to cut out? The worst offenders include fermented foods and aged products (think aged cheeses, cured meats like salami, smoked fish, soy sauce, vinegar, kombucha, sauerkraut), anything that’s been sitting leftover for a long time (day-old meat or broth can accumulate histamine), alcoholic beverages (and I’d recommend you avoid those anyways), and certain fruits/veggies that are naturally high in histamine or act as liberators (tomatoes, spinach, eggplant, avocado, citrus, strawberries, etc.). Even nuts, chocolate, and shellfish are common triggers for histamine hoarders. It’s a long list, and at first glance you might think, “What can I eat then?!”–but remember, this strict phase is typically temporary, just to get things under control.

By eating a diet of mostly fresh, unaged, unfermented foods (for example: fresh meats or fish cooked and eaten immediately, non-citrus fruits like apples or grapes, most fresh vegetables except the high-histamine ones, olive oil for fats, etc.), you drastically cut down the histamine coming in. This often leads to a noticeable drop in symptoms. One clinical study noted that these dietary modifications not only reduced symptoms, but even showed improvements in DAO enzyme parameters–in other words, a low-histamine diet can help reboot your histamine metabolism.

The Low-Histamine Diet: A Temporary Reset

That said, a low-histamine diet is not a sustainable or complete solution. It’s a tool, not a cure. The reality is that this diet can be quite restrictive and difficult to follow long-term. Many people feel better, then get “stuck” eating only a handful of foods, which can lead to nutritional deficits and a pretty dreary culinary life. So, use the diet as an intervention to identify the problem and get some relief, but plan on reintroducing foods and diversifying your diet once you’ve addressed underlying issues. (We’ll talk about reintroducing later–often you can liberalize your diet again after you’ve improved your tolerance.)

Step 2: Support Histamine Breakdown and Build Up Your “Shield”

While you’re lowering the external histamine load, you also want to boost your body’s ability to degrade histamine and stabilize itself. This involves a few angles:

Vitamin C

Nutrients That Support DAO Function

  • Ensure adequate nutrient cofactors for DAO: Certain vitamins and minerals are crucial for DAO production and function. Notably, vitamin B6, vitamin C, copper, and zinc are all needed by DAO to work properly. If you’re deficient in any of these, it can impair your histamine-clearing capacity. For example, a vitamin B6 deficiency is known to reduce DAO activity, and copper is actually a component of the DAO enzyme itself. I often test and replete these nutrients in clients. Vitamin C in particular is essential for histamine issues–it’s a natural antihistamine and has been shown to help break down histamine by increasing DAO activity. It also stabilizes mast cells (the immune cells that release histamine), making them less likely to dump more histamine. I often have people take 500 mg to 2 g of vitamin C per day (in divided doses).

Should You Use DAO Supplements?

  • One pragmatic tool is using DAO supplements. These are capsulized DAO enzymes (typically derived from beans or animals kidneys) that you can take orally with meals. They essentially provide extra DAO in your gut to help degrade the histamine in the food you’re eating. While not a license to eat junk, they can be a game-changer for expanding your diet. If a patient really misses, say, tomatoes or protein powders, I’ll often suggest trying a DAO capsule beforehand. Many report that it significantly blunts their reactions, as the supplemental DAO breaks down a lot of the histamine before it ever enters your bloodstream. It’s not cheap to use regularly, but can greatly improve quality of life (and nutrition variety) for those with severe intolerance.

Stabilize Mast Cells and Reduce Internal Histamine

  • Another strategy is to use natural compounds that make your body less prone to releasing histamine. The primary targets here are mast cells–these are the cells that unleash histamine in response to triggers. Certain supplements can help calm mast cells down. The most famous is quercetin, a bioflavonoid found in foods like onions and apples. Quercetin is a potent mast cell stabilizer; it basically tells those cells “chill out,” reducing the amount of histamine they spew out. Quercetin has also been found to inhibit the enzyme that converts histidine into histamine, so it lowers the total histamine produced, and it can even block histamine receptors to some extent. Many folks with histamine issues find that taking quercetin (500 mg a couple times a day, often alongside vitamin C for synergy) helps with symptoms like hives, asthma, and facial flushing. Other mast cell stabilizing options include luteolin (another flavonoid), black seed oil, and herbs like stinging nettle (which has natural antihistamine properties). These can be adjuncts to consider in a comprehensive plan.

Fixing the Gut Is Essential

  • Heal the gut and rebalance the microbiome: Since so much of histamine metabolism (and production) happens in the gut, fixing any gut dysbiosis or inflammation is central to long-term improvement. This can involve many facets depending on the person–treating SIBO or Candida overgrowth if present, improving digestion, sealing a “leaky gut” intestinal lining, etc. One specific tip: be strategic with probiotics. Probiotics can be a double-edged sword in histamine intolerance. Some bacterial strains actually produce histamine (for instance, certain Lactobacillus strains in fermented foods), while other strains help degrade histamine. You want to choose probiotic strains that are histamine-neutral or histamine-degrading, rather than histamine-producing. Generally, good choices are Bifidobacterium species (like B. longum, B. infantis) and certain Lactobacillus like L. rhamnosus and L. plantarum, which tend not to generate histamine. Strains to be cautious with are ones found in yogurts and fermented products like L. casei, L. reuteri, and L. bulgaricus, as these are associated with histamine production during fermentation. In practice, I’ve seen people worsening their histamine symptoms by taking a generic probiotic or pounding kombucha/kefir for gut health (ironically trying to be healthy but actually adding histamine). Opt instead for a “low-histamine” probiotic formula–there are now products marketed for this, or use single strains that are known to be safe. And of course, incorporate general gut-healing measures: an anti-inflammatory diet, possibly gut lining supports like glutamine or aloe vera, and addressing any infections or imbalances. As the gut lining heals and gut flora normalize, DAO production can improve and overall histamine load from bacterial sources will drop.

When Antihistamines (and Meds) Can Help

  • Consider antihistamines or other medications judiciously: While my focus is on nutritional and lifestyle strategies, pharmaceuticals have their place for symptom management. H1 antihistamine meds (like loratadine, cetirizine) can provide quick relief for symptoms like hives or sneezing. H2 blockers (like famotidine) can help more with stomach-related histamine issues (and interestingly can alleviate some brain-fog in people who react to histamine in the gut). Using these short-term while you implement the foundational fixes is fine. Just be mindful that some over-the-counter antihistamines are sedating and can add to brain fog or fatigue. Always work with a doctor if you integrate medications. In some severe cases (especially if there’s overlap with mast cell activation syndrome), doctors may prescribe mast cell stabilizers like cromolyn sodium or stronger H1/H2 blockers. Those can be necessary tools in tough cases.

Common Mistake That Can Actually Worsen Histamine Intolerance

Now, let’s talk about those traps and pitfalls. I’ve watched many people attempting to self-manage histamine intolerance fall into these, which either slows their progress or even makes things worse. Here are the big ones to watch out for:

Going on a super-restrictive diet indefinitely

  • Eliminating high-histamine foods is useful to get relief, but it’s easy to get stuck there. Some folks end up afraid to eat anything and maintain a very restrictive low-histamine diet for months or years. This can backfire by causing nutrient deficiencies, social isolation, and additional stress (which itself can increase histamine!). Remember, the goal is to increase your tolerance, not live in a dietary bubble forever. Use the elimination diet as a diagnostic and healing tool, but work towards diversifying your diet again once you’ve improved. Staying on too strict a diet for too long can actually make you more sensitive in some cases (your body might down-regulate DAO production if it thinks it “doesn’t need it” because no histamine is coming in). Gradual reintroduction is key once you’ve done the healing work. Don’t fall for the trap of demonizing all high-histamine foods forever–many are quite nutritious (e.g. tomatoes, spinach) and may be fine in moderation once you’re in balance.

Chasing symptoms in isolation

  • As mentioned, histamine intolerance is systemic. If you just treat, say, migraines with painkillers and hives with cortisone cream, without addressing the common root, you’ll forever play whack-a-mole with symptoms. It can be frustrating to connect all your issues to a single cause, but once you do, the healing strategy becomes much clearer. Avoid letting different specialists pawn you off with disparate diagnoses (sinusitis, IBS, eczema, anxiety) and multiple medications. Consider that histamine could tie together all those symptoms–it often does. Don’t let the sporadic nature of symptoms fool you into thinking they’re unrelated coincidences.

Assuming it’s “just allergies” or expecting allergy tests to give answers

  • Many people with histamine intolerance go to an allergist expecting to find a specific allergy. 99% of the time, it comes back negative or inconclusive for true IgE allergies. That’s because histamine intolerance is not an allergic reaction to a particular substance–it’s a problem with clearing a ubiquitous mediator (histamine). The trap here is wasting time on the wrong tests and getting falsely reassured (“All tests are normal, so maybe it’s in my head?”). Instead, do a histamine challenge–a trial of a low-histamine diet–which is effectively the best “test” for histamine intolerance (see how your body responds). Some providers will test DAO blood levels, which can support the diagnosis if low, but it’s not definitive (people with normal DAO can still have intolerance if intake overwhelms breakdown. So, avoid over-relying on traditional allergy workups; they often lead to dead ends in this scenario.

Kombucha Worsens Histamine Intolerance

Overdoing fermented foods and probiotics without strategy

  • This is a big one in the holistic health world. Fermented foods, kombucha, kimchi, yogurt–these are generally healthy for most people, but for histamine-intolerant individuals they can be incredibly harmful. I’ve seen people, in an effort to “heal the gut,” start consuming lots of bone broth, fermented veggies, and probiotic supplements, only to feel exponentially worse. It’s counterintuitive because those things are usually beneficial, but they are loaded with histamine or histamine-producing bacteria. The mistake is not recognizing that your case is an exception to the usual nutritional advice. If you have histamine issues, you must be selective: for example, instead of fermented cabbage (sauerkraut), eat fresh cabbage or take a non-histamine-producing probiotic pill. Instead of long-simmered bone broth (which can accumulate histamine as it cooks for hours, you might do a quick 1-hour broth or use collagen peptides (which provide gut-healing amino acids without the histamine). Don’t blindly follow generic gut-health trends–tailor them to be histamine-safe.

Relying solely on antihistamine meds or supplements as a crutch

  • Another trap is to treat histamine intolerance only by taking antihistamines every day (or quercetin/vitamin C, etc.) while not addressing why you became intolerant. Symptom relievers are fine and often necessary, but if you stop there, you’re essentially putting a bandaid on a leaky dam. The real fix usually requires digging into root causes: repairing the gut, removing triggering foods for a while, correcting deficiencies, etc. I’ve encountered individuals who take high doses of antihistamines around the clock so they can continue their lifestyle/diet unchanged. That might manage symptoms for a time, but it can lead to tolerance (needing higher doses) and doesn’t improve your baseline. Overuse of certain antihistamines can also cause fatigue and cognitive side effects. So yes, use medications or natural antihistamines to get comfortable, but concurrently work on raising your histamine threshold through the deeper interventions we discussed. The goal is not to need daily pills eventually.

Neglecting other factors like stress and hormones

  • Holistic means holistic. If you clean up your diet and take supplements but meanwhile you’re chronically stressed, sleep-deprived, or (if female) your hormones are out of whack, you might hit a wall. Stress, for example, directly triggers histamine release and gut permeability. I’ve seen stress alone provoke major flare-ups. Prioritize stress reduction and quality sleep as part of your plan (meditation, gentle exercise, etc.–whatever lowers your cortisol). And for women, if you suspect something like estrogen dominance or very symptomatic perimenopause, address that; high estrogen without enough progesterone relief can drive histamine issues in a loop. Sometimes supporting hormone balance (with the help of a practitioner) can raise the histamine tolerance significantly. The trap here is focusing 100% on foods and supplements while ignoring lifestyle and internal factors that are feeding into the problem.

Addressing histamine intolerance is admittedly a bit complex, but the reward if enormous.

The key takeaways to remember:

  • Recognize it: If you have a weird mix of symptoms across different body systems that doctors can’t explain, and they get worse with certain foods or during times of stress, consider histamine intolerance. It’s more common than you’d think, and often hiding in plain sight under other diagnoses.

  • Reduce the immediate load: Implement a low-histamine diet trial and see if you improve. This should be mainly diagnostic.

  • Work on the root causes: Improve your DAO function with proper nutrients (B6, copper, vitamin C, etc.), possibly supplement DAO directly when needed, heal your gut, and avoid triggers that you can control (like problematic meds or high-histamine habits). By improving your body’s capacity and lowering its histamine production, you raise that tolerance threshold.

  • Be mindful of the common pitfalls: Don’t get stuck in an avoidance-only pattern–the goal is resilience, not permanent deprivation. And don’t inadvertently sabotage yourself with well-meaning “healthy” additions that aren’t actually healthy for you (like those ferments or random supplements).

The way to fix this now:

You must do things systematically. I’d highly recommend checking out my Histamine Overload Roadmap, which outlines exactly what you should do and take over the course of weeks and months to methodically get rid of your histamine intolerance. You can access it for free as part of my Roadmaps to Health platform:

The Histamine Overload Roadmap

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