
Dr. Malek's Clinical-Grade Slow COMT Roadmap
A clinician-developed protocol for stabilizing dopamine overload, improving sleep and anxiety, and clearing brain fog in COMT-slow individuals.
What You’ll Get
Dr. Malek’s precisely-tuned, step-by-step protocol based on functional neurochemistry
Clear supplement strategies—when to start, what to combine, how to adjust
Targeted nutritional and lifestyle changes that match COMT clearance dynamics
Built-in testing recommendations to guide deeper insight when needed
Immediate PDF download with lifetime access
Why This Roadmap Exists
If you have a slow COMT gene, your brain doesn't clear activating neurotransmitters (like dopamine and norepinephrine) efficiently. The result is:
Overstimulation from stress or supplements
Anxiety, racing thoughts, and restlessness
Insomnia that doesn’t respond to usual sleep support
Emotional swings or overwhelm in day-to-day situations
Brain fog and mental fatigue—especially under pressure
Bona fide estrogen overload
These patterns are rarely recognized by conventional medicine.
This roadmap gives you a clear, non-overstimulating plan for how to stabilize, step by step.
Who This Is For
Anyone with COMT rs4680 A/A or A/G genotype
People who feel worse on B vitamins, multivitamins, or methyl donors
Those struggling with mood instability, paradoxical supplement reactions, or unexplained fatigue
People with Estrogen Overload pictures
Functional medicine practitioners looking for a structured COMT support framework
What’s Inside the Slow COMT Roadmap
Phase 1: Mineral and Nervous System Reset
Build a calmer, more stable baseline by supporting electrolytes and mineral cofactors.Phase 2: Foundational Neurochemical Support
Introduce key nutrients that help stabilize neurotransmitter levels without overstimulation.Phase 3: Dopamine and Methylation Balance
Gradually support dopamine clearance, methylation capacity, and stress recovery pathways.Phase 4: Sleep and Catecholamine Regulation
Target nighttime wakefulness and adrenaline surges with advanced sleep-phase supports.Optional Phase: BH4 and Sulfur Pathway Optimization
For those with lingering sensitivity or neurotransmitter swings, this section provides precision tuning.Final Stage: When and How to Test Further
Know what labs to run if symptoms persist, and how to interpret them through the COMT lens.
Each phase includes clear supplement guidance, food-based strategies, troubleshooting tips, etc.
Why It Works
This roadmap isn’t based on theory.
It reflects the distilled framework I use in clinical settings with patients who have genetically slow COMT function and who’ve struggled for years without answers.
The results are generally better sleep, calmer mood, fewer crashes, and clearer thinking.
It’s not about chasing symptoms. It’s about supporting the real bottlenecks in your neurochemistry.
Price
$99 USD
Secure checkout. Instant access. One-time purchase.
📌 How to Order: Click “Add to Cart,” then complete checkout via the cart icon above.
A clinician-developed protocol for stabilizing dopamine overload, improving sleep and anxiety, and clearing brain fog in COMT-slow individuals.
What You’ll Get
Dr. Malek’s precisely-tuned, step-by-step protocol based on functional neurochemistry
Clear supplement strategies—when to start, what to combine, how to adjust
Targeted nutritional and lifestyle changes that match COMT clearance dynamics
Built-in testing recommendations to guide deeper insight when needed
Immediate PDF download with lifetime access
Why This Roadmap Exists
If you have a slow COMT gene, your brain doesn't clear activating neurotransmitters (like dopamine and norepinephrine) efficiently. The result is:
Overstimulation from stress or supplements
Anxiety, racing thoughts, and restlessness
Insomnia that doesn’t respond to usual sleep support
Emotional swings or overwhelm in day-to-day situations
Brain fog and mental fatigue—especially under pressure
Bona fide estrogen overload
These patterns are rarely recognized by conventional medicine.
This roadmap gives you a clear, non-overstimulating plan for how to stabilize, step by step.
Who This Is For
Anyone with COMT rs4680 A/A or A/G genotype
People who feel worse on B vitamins, multivitamins, or methyl donors
Those struggling with mood instability, paradoxical supplement reactions, or unexplained fatigue
People with Estrogen Overload pictures
Functional medicine practitioners looking for a structured COMT support framework
What’s Inside the Slow COMT Roadmap
Phase 1: Mineral and Nervous System Reset
Build a calmer, more stable baseline by supporting electrolytes and mineral cofactors.Phase 2: Foundational Neurochemical Support
Introduce key nutrients that help stabilize neurotransmitter levels without overstimulation.Phase 3: Dopamine and Methylation Balance
Gradually support dopamine clearance, methylation capacity, and stress recovery pathways.Phase 4: Sleep and Catecholamine Regulation
Target nighttime wakefulness and adrenaline surges with advanced sleep-phase supports.Optional Phase: BH4 and Sulfur Pathway Optimization
For those with lingering sensitivity or neurotransmitter swings, this section provides precision tuning.Final Stage: When and How to Test Further
Know what labs to run if symptoms persist, and how to interpret them through the COMT lens.
Each phase includes clear supplement guidance, food-based strategies, troubleshooting tips, etc.
Why It Works
This roadmap isn’t based on theory.
It reflects the distilled framework I use in clinical settings with patients who have genetically slow COMT function and who’ve struggled for years without answers.
The results are generally better sleep, calmer mood, fewer crashes, and clearer thinking.
It’s not about chasing symptoms. It’s about supporting the real bottlenecks in your neurochemistry.
Price
$99 USD
Secure checkout. Instant access. One-time purchase.
📌 How to Order: Click “Add to Cart,” then complete checkout via the cart icon above.