The Most Comprehensive Methylation Genetics Test Available

Get your full methylation genetics analyzed by a precision-trained clinician—then get the exact supplement plan that fits your biology.

💠 Clinical-Grade Genetic Testing (not sold direct-to-consumer)

💠 29 Essential Genes Affecting Methylation, including MTHFR and COMT

💠 Full Expert Interpretation Report – written by Dr. Malek with customized supplement recommendations with exact dosages

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

🧪 Normally: $549

$499

Get the full KIT + REPORT + SUPPLEMENT PLAN
At $50 OFF.

“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”

One of our clients

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

I work regularly with people who:

  • Feel like their energy, mood, or brain function just don’t match their effort

  • React unpredictably to supplements—sometimes better, sometimes worse

  • Have been chasing answers across doctors, diets, and lab tests without clarity

  • Struggle with inflammation, fatigue, anxiety, or sleep issues that resist treatment

  • Can’t tolerate detox protocols, B vitamins, or “advanced” health plans

  • Sense something deeper is going on—something no one has fully explained

  • Want to understand their body at the foundational level before guessing what to fix

If any of this resonates, there’s a good chance your underlying biochemistry is shaped by genetic factors that haven’t been properly interpreted.

If you’ve tried everything and still feel like something’s off:

Start here.

The Comprehensive Methylation Panel is the one of the most comprehensive methylation-focused genetic tests on the market.

Designed to decode the hidden genetic drivers of your:

  • Fatigue and brain fog

  • Low energy and persistent brain fog

  • Anxiety, irritability, or overstimulation

  • Depression or flat, unresponsive mood

  • Poor tolerance of folate or B12 supplements

  • Elevated homocysteine or cardiovascular risk

  • Estrogen dominance, PMS, or hormone sensitivity

  • Poor detoxification and heightened chemical sensitivity

  • Histamine intolerance or unexplained food reactions

It covers 29 essential Gene SNPs that influence your folate metabolism, B12 metabolism, methylation capacity, homocysteine catabolism, mitochondrial biogenesis, vitamin D utilization, and more.

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

What You'll Discover

Your test includes a focused interpretation of 29 genes central to methylation and its downstream effects, including:

  • Folate Cycle Efficiency (MTHFR, MTHFD1, MTHFS, DHFR) – how effectively you convert folate into active methyl donors

  • B12 Transport & Recycling (MTR, MTRR, TCN1, TCN2, CUBN) – your ability to activate and retain B12 for methylation

  • Homocysteine Clearance & SAMe Production (BHMT, CBS, AHCY) – how efficiently you generate and recycle methyl groups

  • Catecholamine and Hormone Clearance (COMT) – methylation’s role in breaking down dopamine, adrenaline, and estrogens

  • Methylation-Linked Redox Support (SOD2, NQO1) – how methylation connects to antioxidant defense and oxidative stress control

📦 How It Works:

  1. Order your kit online

  2. Receive your cheek swab kit by mail (5–7 days)

  3. Swab and send it back using the prepaid return label

  4. Once your results are ready, I build your report personally.

  5. Receive your custom supplement plan within 3-4 weeks

from $399.00

This level of analysis is not available anywhere else.

Your report is written by a clinician who specializes in complex biochemical cases:

  • NOT outsourced,

  • NOT autogenerated,

  • and NOT something you can get from any lab.

Dr. Malek Hamed

~ Dr. Malek

Why I Built This

I’m a licensed physician, conventionally trained and later specialized in Precision and Genomics-Based Medicine through IFM Functional Medicine. Over the years, I’ve worked with countless patients whose symptoms didn’t improve with standard care—persistent fatigue, anxiety, poor sleep, histamine reactivity, hormone imbalance, or even paradoxical responses to B vitamins and supplements.

In many of these cases, the root issue was impaired methylation. But most genetic tests available today aren’t designed to address this. They overwhelm patients with raw data or superficial summaries, without connecting the dots to a real clinical plan.

I built the Comprehensive Methylation Panel to change that.

This panel focuses exclusively on the 29 genes that define methylation efficiency, homocysteine clearance, B12 and folate handling, hormone and neurotransmitter breakdown, and redox balance—interpreted in a way that is biologically precise and directly actionable.

It’s the same test and interpretive method I use in my private practice when identifying methylation-driven contributors to fatigue, anxiety, sleep disruption, detox bottlenecks, and mood instability.

Get the Panel:

  • After you order, I’ll work on getting your kit shipped out within 1-2 days max. You’ll get a USPS tracking number.

  • Once your results are in and I finish developing your supplement plan, I’ll email those to you and give you access to a free month of my Precision Membership.

    Start figuring out your mystery health problems →

Includes full test kit and expert-prepared supplement plan

Results delivered as PDF to your inbox.

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

If you have any questions at all, please do email me. I am extremely responsive and will help you personally.

If you’re not ready for the full test:

Sign up for my newsletter and get:

  1. $40 off any of my genetic tests

  2. A treasure trove of totally free information on fixing your health using your genetics.