The Most Comprehensive Methylation Genetics Test Available
Get your full methylation genetics analyzed by a precision-trained clinician—then get the exact supplement plan that fits your biology.
💠 Clinical-Grade Genetic Testing (not sold direct-to-consumer)
💠 26 Essential Genes Affecting Methylation, including MTHFR and COMT
💠 Expert Interpretation Video – I’ll record myself analyzing your genetics and recommend supplements with exact dosages (and lifestyle changes)
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of our clients
Get $100 OFF when you order three kits (automatically applied at checkout)
Check out the sample report here for the $499 option.
Our Comprehensive Methylation Panel + COMT testing is one of the most in-depth genetic methylation tests on the market. This test looks at 26 gene SNPs that are highly relevant to the process of methylation. This has the potential to help you fix your:
Chronic fatigue
Memory issues
Mood issues
Migraines
Detox issues
Chronic allergies and hypersensitivities
And much more.
Your genetic results include a summary with personalized supplement recommendations written by our head physician, Dr. Malek (optional).
Get your results in 5 steps:
Order your kit.
Receive your kit, usually within 5-7 business days via USPS (tracking information provides upon shipment).
Perform your cheek swab.
Mail your kit back to the lab (free return shipping label included).
Get your results sent to your email with personalized recommendations based on your genetics (approximately 2-3 weeks after we receive your sample in the lab).
This is one of the most comprehensive methylation tests on the market—for one of the lowest prices out there. It offers much more than just a basic MTHFR test. Full list of gene SNPs (with exact rsids) below!
Learn more about why it’s so important to test for more than just MTHFR.
For the ultimate health unlock, consider ordering this test along with Mood and Alzheimer’s/Autophagy in combination.
Not sure if this kit is right for you? Email us
Genes (with exact rsids):
AHCY (rs13043752)
BHMT (rs3733890)
CBS (rs234706)
CUBN (rs1801222)
DHFR (rs70991108)
FOLR1 (rs2071010)
GC (rs2282679)
MAT1A (rs7087728)
MTHFD1 (rs2236225)
MTHFR: A1298C (rs1801131)
MTHFR: C677T (rs1801133)
MTHFS (rs898436)
MTR (rs1805087)
MTRR: A66G (rs1801394)
NFE2L2 (rs6721961)
NPC1L1 (rs2072183)
NQO1 (rs1800566)
PPARGC1A (rs8192678)
SIRT1 (rs1467568)
SLC19A1 (rs1051266)
SOD2 (rs4880)
TCN1 (rs526934)
TCN2 (rs1801198)
TFAM (rs1937)
VDR (rs2228570)
COMT rs4680 (rs4680)
$499
Get the full KIT + REPORT + VIDEO ANALYSIS
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of my clients
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of our clients
Get $100 OFF when you order three kits (automatically applied at checkout)
Check out the sample report here for the $499 option.
Our Comprehensive Methylation Panel + COMT testing is one of the most in-depth genetic methylation tests on the market. This test looks at 26 gene SNPs that are highly relevant to the process of methylation. This has the potential to help you fix your:
Chronic fatigue
Memory issues
Mood issues
Migraines
Detox issues
Chronic allergies and hypersensitivities
And much more.
Your genetic results include a summary with personalized supplement recommendations written by our head physician, Dr. Malek (optional).
Get your results in 5 steps:
Order your kit.
Receive your kit, usually within 5-7 business days via USPS (tracking information provides upon shipment).
Perform your cheek swab.
Mail your kit back to the lab (free return shipping label included).
Get your results sent to your email with personalized recommendations based on your genetics (approximately 2-3 weeks after we receive your sample in the lab).
This is one of the most comprehensive methylation tests on the market—for one of the lowest prices out there. It offers much more than just a basic MTHFR test. Full list of gene SNPs (with exact rsids) below!
Learn more about why it’s so important to test for more than just MTHFR.
For the ultimate health unlock, consider ordering this test along with Mood and Alzheimer’s/Autophagy in combination.
Not sure if this kit is right for you? Email us
Genes (with exact rsids):
AHCY (rs13043752)
BHMT (rs3733890)
CBS (rs234706)
CUBN (rs1801222)
DHFR (rs70991108)
FOLR1 (rs2071010)
GC (rs2282679)
MAT1A (rs7087728)
MTHFD1 (rs2236225)
MTHFR: A1298C (rs1801131)
MTHFR: C677T (rs1801133)
MTHFS (rs898436)
MTR (rs1805087)
MTRR: A66G (rs1801394)
NFE2L2 (rs6721961)
NPC1L1 (rs2072183)
NQO1 (rs1800566)
PPARGC1A (rs8192678)
SIRT1 (rs1467568)
SLC19A1 (rs1051266)
SOD2 (rs4880)
TCN1 (rs526934)
TCN2 (rs1801198)
TFAM (rs1937)
VDR (rs2228570)
COMT rs4680 (rs4680)
I work regularly with people who:
Feel like their energy, mood, or brain function do not match their effort
React unpredictably to supplements—sometimes better, sometimes worse
Have been chasing answers across doctors, diets, and lab tests without clarity
Struggle with inflammation, fatigue, anxiety, or sleep issues that resist treatment
Cannot tolerate detox protocols, B vitamins, or “advanced” health plans
Sense something deeper is going on
Want to understand their body at the foundational level before guessing what to fix
If any of this resonates, there’s a good chance your underlying biochemistry is shaped by genetic factors that haven’t been properly interpreted.
If you’ve already gone through a lot but haven’t touched methylation:
Start here.
My Comprehensive Methylation Panel is genuinely one of the most comprehensive methylation-focused genetic tests on the market.
Designed to uncover the hidden genetic drivers of your:
Fatigue and brain fog
Low energy and persistent brain fog
Anxiety, irritability, or overstimulation
Depression or flat, unresponsive mood
Poor tolerance of folate or B12 supplements
Elevated homocysteine or cardiovascular risk
Estrogen dominance, PMS, or hormone sensitivity
Poor detoxification and heightened chemical sensitivity
Histamine intolerance or unexplained food reactions
It covers 26 essential Gene SNPs that influence your folate metabolism, B12 metabolism, methylation capacity, homocysteine catabolism, mitochondrial biogenesis, vitamin D utilization, and more.
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of our clients
Get $100 OFF when you order three kits (automatically applied at checkout)
Check out the sample report here for the $499 option.
Our Comprehensive Methylation Panel + COMT testing is one of the most in-depth genetic methylation tests on the market. This test looks at 26 gene SNPs that are highly relevant to the process of methylation. This has the potential to help you fix your:
Chronic fatigue
Memory issues
Mood issues
Migraines
Detox issues
Chronic allergies and hypersensitivities
And much more.
Your genetic results include a summary with personalized supplement recommendations written by our head physician, Dr. Malek (optional).
Get your results in 5 steps:
Order your kit.
Receive your kit, usually within 5-7 business days via USPS (tracking information provides upon shipment).
Perform your cheek swab.
Mail your kit back to the lab (free return shipping label included).
Get your results sent to your email with personalized recommendations based on your genetics (approximately 2-3 weeks after we receive your sample in the lab).
This is one of the most comprehensive methylation tests on the market—for one of the lowest prices out there. It offers much more than just a basic MTHFR test. Full list of gene SNPs (with exact rsids) below!
Learn more about why it’s so important to test for more than just MTHFR.
For the ultimate health unlock, consider ordering this test along with Mood and Alzheimer’s/Autophagy in combination.
Not sure if this kit is right for you? Email us
Genes (with exact rsids):
AHCY (rs13043752)
BHMT (rs3733890)
CBS (rs234706)
CUBN (rs1801222)
DHFR (rs70991108)
FOLR1 (rs2071010)
GC (rs2282679)
MAT1A (rs7087728)
MTHFD1 (rs2236225)
MTHFR: A1298C (rs1801131)
MTHFR: C677T (rs1801133)
MTHFS (rs898436)
MTR (rs1805087)
MTRR: A66G (rs1801394)
NFE2L2 (rs6721961)
NPC1L1 (rs2072183)
NQO1 (rs1800566)
PPARGC1A (rs8192678)
SIRT1 (rs1467568)
SLC19A1 (rs1051266)
SOD2 (rs4880)
TCN1 (rs526934)
TCN2 (rs1801198)
TFAM (rs1937)
VDR (rs2228570)
COMT rs4680 (rs4680)
Your test includes a focused interpretation of 26 genes central to methylation and its downstream effects, including:
Folate Cycle Efficiency (MTHFR, MTHFD1, MTHFS, DHFR) – how effectively you convert folate into active methyl donors
B12 Transport & Recycling (MTR, MTRR, TCN1, TCN2, CUBN) – your ability to activate and retain B12 for methylation
Homocysteine Clearance & SAMe Production (BHMT, CBS, AHCY) – how efficiently you generate and recycle methyl groups
Catecholamine and Hormone Clearance (COMT) – methylation’s role in breaking down dopamine, adrenaline, and estrogens
Methylation-Linked Redox Support (SOD2, NQO1) – how methylation connects to antioxidant defense and oxidative stress control
📦 How It Works:
Order your kit online
Receive your cheek swab kit by mail (delivers in usually 5–7 days)
Swab and send it back using the prepaid return label
Once your results are ready, I (Dr. Malek) will record myself analyzing your genetic data.
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of our clients
Get $100 OFF when you order three kits (automatically applied at checkout)
Check out the sample report here for the $499 option.
Our Comprehensive Methylation Panel + COMT testing is one of the most in-depth genetic methylation tests on the market. This test looks at 26 gene SNPs that are highly relevant to the process of methylation. This has the potential to help you fix your:
Chronic fatigue
Memory issues
Mood issues
Migraines
Detox issues
Chronic allergies and hypersensitivities
And much more.
Your genetic results include a summary with personalized supplement recommendations written by our head physician, Dr. Malek (optional).
Get your results in 5 steps:
Order your kit.
Receive your kit, usually within 5-7 business days via USPS (tracking information provides upon shipment).
Perform your cheek swab.
Mail your kit back to the lab (free return shipping label included).
Get your results sent to your email with personalized recommendations based on your genetics (approximately 2-3 weeks after we receive your sample in the lab).
This is one of the most comprehensive methylation tests on the market—for one of the lowest prices out there. It offers much more than just a basic MTHFR test. Full list of gene SNPs (with exact rsids) below!
Learn more about why it’s so important to test for more than just MTHFR.
For the ultimate health unlock, consider ordering this test along with Mood and Alzheimer’s/Autophagy in combination.
Not sure if this kit is right for you? Email us
Genes (with exact rsids):
AHCY (rs13043752)
BHMT (rs3733890)
CBS (rs234706)
CUBN (rs1801222)
DHFR (rs70991108)
FOLR1 (rs2071010)
GC (rs2282679)
MAT1A (rs7087728)
MTHFD1 (rs2236225)
MTHFR: A1298C (rs1801131)
MTHFR: C677T (rs1801133)
MTHFS (rs898436)
MTR (rs1805087)
MTRR: A66G (rs1801394)
NFE2L2 (rs6721961)
NPC1L1 (rs2072183)
NQO1 (rs1800566)
PPARGC1A (rs8192678)
SIRT1 (rs1467568)
SLC19A1 (rs1051266)
SOD2 (rs4880)
TCN1 (rs526934)
TCN2 (rs1801198)
TFAM (rs1937)
VDR (rs2228570)
COMT rs4680 (rs4680)
This level of analysis is not available anywhere else.
Your video analysis is produced by a clinician who specializes in complex biochemical cases:
I do NOT outsource or autogenerate your analysis. Nor is this something you can get from any lab.
~ Dr. Malek
Why I Built This
I’m a licensed physician, conventionally trained and later trained in Precision and Genomics-Based Medicine through IFM (the Institute for Functional Medicine) and GX Sciences. Over the years, I’ve worked with countless patients whose symptoms absolutely did not improve with standard care: Persistent fatigue, anxiety, poor sleep, histamine reactivity, hormone imbalance, paradoxical responses to B vitamins and supplements, etc. etc. etc.
In many of these cases, the root issue was impaired methylation. But most methylation tests are (in my frank opinion) far too superficial to be of much use here.
My Comprehensive Methylation Panel is not so.
This panel focuses on the 26 top genes that affect methylation efficiency, homocysteine clearance, B12 and folate handling, hormone and neurotransmitter breakdown, mitochondrial function, and redox balance, interpreted in a way that is biologically precise and directly actionable.
This is precisely what I would do in my private practice when trying to identify genetic methylation-driven contributors to fatigue, anxiety, sleep disruption, detox bottlenecks, and mood instability.
Get the Panel:
After you order, I’ll work on getting your kit shipped out within 1-2 days max. You’ll get a USPS tracking number.
Once your results are in and I finish developing your supplement plan and recording your video analysis, I’ll email those to you directly.
Start figuring out your mystery health problems →
Includes full test kit and expert-prepared video analysis/supplement plan
Results delivered to your inbox.
“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”
— One of our clients
Get $100 OFF when you order three kits (automatically applied at checkout)
Check out the sample report here for the $499 option.
Our Comprehensive Methylation Panel + COMT testing is one of the most in-depth genetic methylation tests on the market. This test looks at 26 gene SNPs that are highly relevant to the process of methylation. This has the potential to help you fix your:
Chronic fatigue
Memory issues
Mood issues
Migraines
Detox issues
Chronic allergies and hypersensitivities
And much more.
Your genetic results include a summary with personalized supplement recommendations written by our head physician, Dr. Malek (optional).
Get your results in 5 steps:
Order your kit.
Receive your kit, usually within 5-7 business days via USPS (tracking information provides upon shipment).
Perform your cheek swab.
Mail your kit back to the lab (free return shipping label included).
Get your results sent to your email with personalized recommendations based on your genetics (approximately 2-3 weeks after we receive your sample in the lab).
This is one of the most comprehensive methylation tests on the market—for one of the lowest prices out there. It offers much more than just a basic MTHFR test. Full list of gene SNPs (with exact rsids) below!
Learn more about why it’s so important to test for more than just MTHFR.
For the ultimate health unlock, consider ordering this test along with Mood and Alzheimer’s/Autophagy in combination.
Not sure if this kit is right for you? Email us
Genes (with exact rsids):
AHCY (rs13043752)
BHMT (rs3733890)
CBS (rs234706)
CUBN (rs1801222)
DHFR (rs70991108)
FOLR1 (rs2071010)
GC (rs2282679)
MAT1A (rs7087728)
MTHFD1 (rs2236225)
MTHFR: A1298C (rs1801131)
MTHFR: C677T (rs1801133)
MTHFS (rs898436)
MTR (rs1805087)
MTRR: A66G (rs1801394)
NFE2L2 (rs6721961)
NPC1L1 (rs2072183)
NQO1 (rs1800566)
PPARGC1A (rs8192678)
SIRT1 (rs1467568)
SLC19A1 (rs1051266)
SOD2 (rs4880)
TCN1 (rs526934)
TCN2 (rs1801198)
TFAM (rs1937)
VDR (rs2228570)
COMT rs4680 (rs4680)
If you have any questions at all, please do email me. I am extremely responsive and will help you personally.
If you’re not ready for the full test:
Sign up for my newsletter and get:
$40 off any of my genetic tests
A treasure trove of totally free information on fixing your health using your genetics.