The Most Comprehensive Methylation Genetics Test Available

Get your full methylation genetics analyzed by a precision-trained clinician—then get the exact supplement plan that fits your biology.

💠 Clinical-Grade Genetic Testing (not sold direct-to-consumer)

💠 29 Essential Genes Affecting Methylation, including MTHFR and COMT

💠 Expert Interpretation Video – I’ll record myself analyzing your genetics and recommend supplements with exact dosages (and lifestyle changes)

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

$499

Get the full KIT + REPORT + VIDEO ANALYSIS

“Wow, All I can say is this test has been incredibly helpful for both my daughter and my wife. It’s uncovered some major issues that we had not been able to diagnose with standard tests.”

One of our clients

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

I work regularly with people who:

  • Feel like their energy, mood, or brain function do not match their effort

  • React unpredictably to supplements—sometimes better, sometimes worse

  • Have been chasing answers across doctors, diets, and lab tests without clarity

  • Struggle with inflammation, fatigue, anxiety, or sleep issues that resist treatment

  • Cannot tolerate detox protocols, B vitamins, or “advanced” health plans

  • Sense something deeper is going on

  • Want to understand their body at the foundational level before guessing what to fix

If any of this resonates, there’s a good chance your underlying biochemistry is shaped by genetic factors that haven’t been properly interpreted.

If you’ve already gone through a lot but haven’t touched methylation:

Start here.

My Comprehensive Methylation Panel is genuinely one of the most comprehensive methylation-focused genetic tests on the market.

Designed to uncover the hidden genetic drivers of your:

  • Fatigue and brain fog

  • Low energy and persistent brain fog

  • Anxiety, irritability, or overstimulation

  • Depression or flat, unresponsive mood

  • Poor tolerance of folate or B12 supplements

  • Elevated homocysteine or cardiovascular risk

  • Estrogen dominance, PMS, or hormone sensitivity

  • Poor detoxification and heightened chemical sensitivity

  • Histamine intolerance or unexplained food reactions

It covers 29 essential Gene SNPs that influence your folate metabolism, B12 metabolism, methylation capacity, homocysteine catabolism, mitochondrial biogenesis, vitamin D utilization, and more.

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

Your test includes a focused interpretation of 29 genes central to methylation and its downstream effects, including:

  • Folate Cycle Efficiency (MTHFR, MTHFD1, MTHFS, DHFR) – how effectively you convert folate into active methyl donors

  • B12 Transport & Recycling (MTR, MTRR, TCN1, TCN2, CUBN) – your ability to activate and retain B12 for methylation

  • Homocysteine Clearance & SAMe Production (BHMT, CBS, AHCY) – how efficiently you generate and recycle methyl groups

  • Catecholamine and Hormone Clearance (COMT) – methylation’s role in breaking down dopamine, adrenaline, and estrogens

  • Methylation-Linked Redox Support (SOD2, NQO1) – how methylation connects to antioxidant defense and oxidative stress control

📦 How It Works:

  1. Order your kit online

  2. Receive your cheek swab kit by mail (delivers in usually 5–7 days)

  3. Swab and send it back using the prepaid return label

  4. Once your results are ready, I (Dr. Malek) will record myself analyzing your genetic data.

from $399.00

This level of analysis is not available anywhere else.

Your video analysis is produced by a clinician who specializes in complex biochemical cases:

I do NOT outsource or autogenerate your analysis. Nor is this something you can get from any lab.

Dr. Malek Hamed

~ Dr. Malek

Why I Built This

I’m a licensed physician, conventionally trained and later trained in Precision and Genomics-Based Medicine through IFM (the Institute for Functional Medicine) and GX Sciences. Over the years, I’ve worked with countless patients whose symptoms absolutely did not improve with standard care: Persistent fatigue, anxiety, poor sleep, histamine reactivity, hormone imbalance, paradoxical responses to B vitamins and supplements, etc. etc. etc.

In many of these cases, the root issue was impaired methylation. But most methylation tests are (in my frank opinion) far too superficial to be of much use here.

My Comprehensive Methylation Panel is not so.

This panel focuses on the 29 top genes that affect methylation efficiency, homocysteine clearance, B12 and folate handling, hormone and neurotransmitter breakdown, mitochondrial function, and redox balance, interpreted in a way that is biologically precise and directly actionable.

This is precisely what I would do in my private practice when trying to identify genetic methylation-driven contributors to fatigue, anxiety, sleep disruption, detox bottlenecks, and mood instability.

Get the Panel:

  • After you order, I’ll work on getting your kit shipped out within 1-2 days max. You’ll get a USPS tracking number.

  • Once your results are in and I finish developing your supplement plan and recording your video analysis, I’ll email those to you directly.

    Start figuring out your mystery health problems →

Includes full test kit and expert-prepared video analysis/supplement plan

Results delivered to your inbox.

MTHFRSolve Comprehensive Methylation Panel + COMT Testing
from $399.00

If you have any questions at all, please do email me. I am extremely responsive and will help you personally.

If you’re not ready for the full test:

Sign up for my newsletter and get:

  1. $40 off any of my genetic tests

  2. A treasure trove of totally free information on fixing your health using your genetics.